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Reagents

Updated
9 Nov 2026

Blood grouping anti-sera

Blood grouping reagents for ABO and RhD typing: SICHERCLONE monoclonal anti-A, anti-B and anti-D, plus anti-AB and anti-human globulin.

SICHERCLONE anti-B, anti-D, anti-A and anti-AB dropper bottles
SICHERCLONE blood grouping anti-sera.

SICHERCLONE reagents are murine monoclonal antibodies for ABO and RhD blood grouping.

How ABO and RhD grouping works

People are grouped as A, B, AB or O according to the antigens on their red cells. The A and B antigens are built on a precursor called H substance: adding N-acetylgalactosamine gives A activity, and adding galactose gives B activity.

SICHERCLONE Anti-D combines monoclonal IgM and IgG anti-D. IgM antibodies are larger and have ten binding sites, so they can bridge the gap between red cells and agglutinate them; the IgG component supports detection of weak D types in the same test.

Reagents

Download the SICHERCLONE brochure (PDF)

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